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At the TVCS
meeting in Royal Berkshire Hospital on the 11th March 2005, Christine
Payne stated that at present there are two major companies, (Surepath
/ Cytyc) offering LBC for use in the NHSCSP. Both procedures can
also be used for the preparation of non-gynae.
The main advantages
of LBC are:
" Maximising the cellularity of the sample
" Removal of excess blood/ mucus
" Excellent fixation
" One representative slide
" Extra material available for further tests, immunocytochemistry
and teaching
The disadvantage
of LBC is the cost, but the cost must be weighed against the benefits
for medical and BMS time.
Samples that could be processed are:
" Exfoliative/Aspiration samples
" Urines
" Sputa,Bronchial washings/brushings
" Body Fluids
" FNA - Head and Neck, Lymph Nodes, Lung, Liver, Breast
At this hospital
laboratory most samples can be diagnosed purely on the ThinPrep
sample. ENT routinely
use LBC only with the exception of
Thyroid Aspirates, as colloid is difficult to evaluate, and LBC
only is not recommended.
On other FNA sites usually both air-dried slides and LBC are taken.
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