Thames Valley Cytology Society

Volume 4 Issue 2
June 2001

 

NAC Conference at Warwick University

Report by Marilyn Catlow, Northwick Park Hospital

 

Technical EQA - What is a good Papanicolaou Stain?

A NHSCSP working party has formulated a national scheme for a Technical EQA, for which approval will be sought in the coming year. Mike Rowell gave us a taster of what this would mean. he gave us a few pointers which should help us apply self criticism to our staining parameters and survive EQA scrutiny.

  1. Select only negative slides, as there is a bias towards calling a smear well-stained if dyskaryosis have been detected.
  2. Select single cells in a well-fixed area with little or no background inflammatory esudate.
  3. Look at nuclear colouration, differentiation and contrast.
  4. Look at cytolplasmic colour balance, intensity of individual colours, and translucency.

Mike projected ten slides of varying staining qualtiy. He invited two members of the executive panel to act as 'expert markers', and us delegates were given a sheet on which we rated this staining quality. We can be encouraged that we are consistent at assessing what a good Pap stain is. Most of the people I asked had agreed with the panel markers to one mark (out of ten) on the slides projected.

Those labs that have been involved in the pilot scheme affirm the value of the scheme. they claim that there has been an overall improvement in standards, that it prevents isolated over-confidence, and that friendly rivalry is a good thing.

Gary Gill, who writes with great authority (especially about stains) to the Cytopathnet-L listserve, was asked for a prescription of the 'best possible' Pap stained smear - if it exists. His answer was that 'herding cats is simpler than coming to consensus on Pap stain quality'.

Mike agreed that personal preference would always win.